Effects of paraquat dichloride on adult male wistar rat. an approach in the toxicity of body weights and hematological tissues
نویسندگان
چکیده
The main objective of the experiment is aimed to examine impact paraquat dichloride on body weights adult male Wistar rats as well in their haematological tissues. total number was 48 and divided into 4 groups 12 each. 1st group (Test 1) served control. other three experimental which administered. are 2nd 2), 3rd 3) 4th 4) received doses 10 mg/kg b.wt/per oral/day, 20 oral/day 40 respectively. carried out for a time duration 42 days. mean values weights, erythrocyte indices, count (TEC), leucocyte (TLC) Hb concentrations were significantly (P<0.05) decreased Test 2, 3 rats, excluding packed cell volume (PCV), comparison control groups. Outcomes observations from hematological parameters bone marrow revealed toxicity tissues resulting anemia hypoplasia eventually leads failure extensively hematopoietic system following long term exposure high concentration.
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ژورنال
عنوان ژورنال: Journal of analytical & pharmaceutical research
سال: 2022
ISSN: ['2473-0831']
DOI: https://doi.org/10.15406/japlr.2022.11.00394